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Email: si@lau.edu.lb

SUMMER COURSE 2010

Biomedical Informatics: Foundations and Research Directions

“Under the patronage of H.E. Dr. Mohamad Khalife, Minister for Health”

July 5-10, 2010
Lebanese American University


The Summer School is organized by the Software Institute and the School of Arts and Sciences.

Co-Sponsors

    • Lebanese National Council for Scientific Research
    • Philips Middle East
    • Arab Computer Society
    • Software Design

    Background and Objectives

    This Summer School will offer a one-week intensive course, given by world-class experts, on the foundations of Biomedical Informatics and some research directions in this area. Biomedical Informatics is the study of information and computation in biology and health. It focuses on studying and managing information and behavior that is related to decisions in order to develop computational methods and use them to generate knowledge. This scientific area is multidisciplinary and involves knowledge and techniques from Computer Science and Information Technology (IT), Computer and Electrical Engineering, Biology, and Medicine. Biomedical Informatics covers computational techniques and information technologies that can be used for applications such as medical diagnosis, clinical decision making, personalized medicine, molecular biology, and health care systems. Progress in this field will lead to improvement in the quality of medical treatment and health services.

    Expertise in the field of Biomedical Informatics is lacking in Lebanon and the region in terms of university teaching, research, IT development, and health care services and management. This Summer School intends to be a step towards filling this gap. It is intended to be a capacity building activity targeting both academicians and senior IT professionals. The objectives of this summer school are:

    • To build teaching capacity in the field of Biomedical Informatics.
    • To build research capacity in Biomedical Informatics.
    • To facilitate forming Biomedical Informatics research groups, locally and regionally, with possible international collaboration.
    • To encourage cross-disciplinary Biomedical Informatics research in university graduate programs.
    • To build capacity in professional IT organizations.
    • To pave the way for technology and knowledge transfer into health care institutions.

     

    Course Outline and Lecturers

    Tentative subjects are as follows:

    Sub-area Lecturer

    Medicine for scientists and engineers – a brief survey of healthcare

    • Language of Medicine
    • The Clinical Process
    • Healthcare Systems
    • Medical Records
    • Procedural Medicine/Surgical Practice
    • Evidence Based Medicine/Medical Decision Making
    • Quality Improvement/Patient Safety
    • Biomedical Research: Basic/Clinical/Translational
    • Medical Imaging Informatics

    Dr. Bruce Bray,
    Professor of Biomedical Informatics,
    School of Medicine, University of Utah

    Clinical informatics

    • Medical decision making: Rising volumes of data and information; What information do clinicians need? Clinical decision support systems
    • Clinical computing systems: Foundational; Departmental; Electronic medical record systems; Research systems
    • Implementing and operating clinical computing systems: Architecture of hospital information systems; The art and science of implementation; The critical value of skillful day-to-day operations
    • Is there evidence clinical computing does more good than harm?
    • What does the future hold for clinical informatics? Natural language processing; Improved interface and match to human workflow; Building on EMR infrastructure; Health information exchange; Global examples of HIT excellence

    Dr. Thomas Payne
    Medical Director, IT Services
    School of Medicine,
    University of Washington

    Computing for Translational Science and Personalized Medicine

    We will conduct case studies of translating recent genetic and bimolecular discoveries tests, data and information to the practice of personalized medicine. Participants will be introduced to technology infrastructure, biomedical informatics methods, and processes and tools designed to produce precise, preventive and personalized healthcare information. Academics, researchers, graduate students and professionals will learn how computer science and engineering is rapidly transforming health care by the use of the patient’s genetic and molecular data. In addition, health care providers, hospital administrators, and health care policy officials attending the program will be introduced to the underlying principles of personalized medicine and the biomedical science and informatics critical to its’ success. Lectures, hands on demonstrations and evening discussions will cover:

    • Introduction to Personalized Medicine
    • Creating a biomedical informatics infrastructure for translational science
    • Methods of biomedical informatics for Translational Science
    • Raw data to Clinical Knowledge: What does biomedical informatics deliver to physicians
    • Diagnostics, Prognosis and Treatment in Personalized Medicine

    Dr. Peter Tonellato,
    Director of the Laboratory for Personalized Medicine in the Center for Biomedical Informatics at Harvard Medical School,
    Harvard University

    Computational biology and bioinformatics

    The sequencing and deep resequencing of complete genomes has created an unprecedented deluge of data that needs to be analyzed, annotated, catalogued, parsed, deciphered, and stored. Bioinformatics is playing a crucial role in the search, analysis, and the storage of the biomolecular sequence and structure data. After a brief introduction to molecular biology, the course gives an overview of bioinformatics and computational biology.

    Topics surveyed include: the analysis of macromolecular sequences (search, alignment), databases, genetic linkage and association including genome-wide association studies, phylogenetics, and RNA structure prediction, gene expression arrays, and next-generation sequencing.

    The classes will demonstrate visualization packages for bioinformatics algorithms. The hands-on exercises using online publicly available tools will enhance the understanding of the common bioinformatics tasks. Participants can access http://www.cs.sjsu.edu/faculty/khuri/LAU_2010/ for notes, esercises, etc… before the lectures.

    Dr. Sami Khuri,
    Professor of Computer Science,
    San José State University

    Detailed Schedule

    Mon. July 5

     

    Thurs. July 8

     

     8:45

    Clinical Informatics I
    Dr. Thomas Payne

      8:30

    Comp for Trans Sc. & Pers Medicine III
    Lecture: Predicting Personalized Medicine

     10:30

    Coffee break

      10:30

    Coffee break

     11:00

    Clinical Informatics II

      11:00

    Computing for Translational Sc. & Personalized Medicine IV
    Session 2: Demo: Clinical Avatar App Exercises 1-3.

     13:00

    Lunch

      13:00

    Lunch

     14:00

    Clinical Informatics III

      14:00

    Computing for Translational Sc. & Personalized Medicine V
    Lecture: Open Issues in Pers. Medicine
    Session 3: Demo: i2b2 Database & Clinical Avatars

     15:00

    Formal Opening Session

     

     

    15:45

    Coffee break

      16:00

    Coffee break

    16:00 – 18:00

    Clinical Informatics IV

      16:30

    Computing for Translational Sc. & Personalized Medicine VI
    Lecture: Final Thoughts and Q&A

     

     

      18:30 – 19:30

    Coffee-Shop Discussion

    Tues. July 6

     

    Fri. July 9

     

      8:30

    Clinical Informatics V

       8:30

    Computational Biology & Bioinformatics I
    Dr. Sami Khuri

     10:30

    Coffee break

      10:30

    Coffee break

     11:00

    Clinical Informatics VI

      11:00

    Computational Biology & Bioinformatics II

     13:00

    Lunch

      13:00

    Lunch

     14:00

    Medicine for Scientists & Engineers I
    Dr. Bruce Bray

      14:00

    Computational Biology & Bioinformatics III

     15:30

    Coffee break

      15:30

    Coffee break

    16:00- 18:00

    Medicine for Scientists & Engineers II

      16:00 – 18:00

    Computational Biology & Bioinformatics IV

     

     

     

     

    Wedn. July 7

     

    Sat. July 10

     

      8:30

    Medicine for Scientists & Engineers III

       8:30

      Computational Biology and Bioinformatics V

      10:30

    Coffee break

      10:30

      Coffee break

      11:00

    Medicine for Scientists & Engineers IV

      11:00

      Computational Biology and Bioinformatics VI

      13:00

    Lunch

      13:00

      Lunch

      14:00

    Computing for Translational Sc. & Personalized Medicine I
    Lecture: ‘Introduction to Trans Medicine’
    Hand outs, discuss demos and exercises
    Dr. Peter Tonellato

      14:00

      Computational Biology and Bioinformatics VII

      16:00

    Coffee break

      15:30

      Coffee break

      16:30

    Computing for Translational Sc. & Personalized Medicine II
    Lecture: ‘Genome Reduction’
    Session 1: Demo: Identifying Genetic Variation Exercises 1 and 2.

      15:45 -  17:30

    Computational Biology and Bioinformatics VIII

      18:30 – 19:30

    Coffee-Shop Discussion

     

     

    Who Should Attend

    Expected participants are: university academics, researchers, graduate students, and professionals from IT and health organizations, all with appropriate computing background.

    Certificate

    A certificate of attendance will be provided.

    Dates, Time and Place

    Dates: July 5 - 10, 2010
    Time: 8:30 AM - 6:00 PM
    Place: LAU, Beirut Campus

    Registration, Fees and Deadlines

    To register, please fill out the registration form below or email the requested information to: si@lau.edu.lb by April 30.

    Registration fees are $750 per person (includes lunch, coffee breaks, and handouts).

    Payment from outside or inside Lebanon should be made by making a BANK TRANSFER to LAU’s account (please include your name and ‘summer school BMI’ in the transfer form):

    HSBC Bank Middle East
    Ras Beirut Branch
    LAU A/C# 003-024395-100
    Swift Code: BBMELBBX
    IBAN # LB42000700000000003024395100

    Payment inside Lebanon can be made directly at LAU, Beirut, Business Office, Irwin Hall, Ground floor (Regular opening hours are 9:00 AM - 12:00 Noon and 1:30 PM - 2:30 PM).

    Special registration grants are available on need basis. The number of these grants is limited and will depend on sponsors’ donations. Those who feel that they qualify for a registration grant are asked to send their request and justification by email to si@lau.edu.lb.

    The deadline for registration and receiving payments is April 30, or until the class is full (limited places).

    Accommodation

    We will arrange for accommodation in nearby hotels at reasonable prices. Details will be announced later.

    Visa

    Citizens of many countries can get a visa at the Beirut International Airport. After you register, if you need our help to get a visa from the Lebanese Embassy in your country, please let us know at si@lau.edu.lb and fax us a copy of your passport to +961 1 867098 (Attention Dr. Nashat Mansour).

    About Lebanon

    You may find more information on Lebanon in the following websites:

    General Information

    Weather and Dress
    The weather in Julyis warm and ideal for the beach. You can find more information about the weather in the sites listed at ”About Lebanon.”

    Currency and Credit Cards
    In Lebanon, you can use lebanese currency or U.S. Dollars. Currency exchange can be freely made at banks or at small exchange shops (many of them in Beirut). Please note that credit cards are not as commonly used in Lebanon as in the U.S. and Europe. They are accepted mostly at large establishments.

    Language
    Arabic is Lebanon’s official language. But many Lebanese people also speak English and French.

    Contact us at: si@lau.edu.lb